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This study focuses on mechanisms of reciprocity between DGTS
2020-08-04
This study focuses on mechanisms of reciprocity between DGTS and PC in fungi during Pi starvation. We report changes in expression of the BTA1 gene and two PC biosynthesis genes during phosphate starvation of F. velutipes culture. We describe the deduced amino somatostatin receptor sequence and geno
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Other membrane currents are affected as well
2020-08-04
Other membrane currents are affected as well. Some studies have provided evidence that sulfonylureas, in addition to blocking KATP channels, also inhibit chloride and calcium channels. GLYB has been shown to almost inhibit the current generated by Na+–K+ pumps in a concentration-dependent manner (wi
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OGT complexes obtained with peptide substrates that bind in
2020-08-04
OGT complexes obtained with peptide substrates that bind in the TPR lumen of the 4.5 construct have provided important insight into how OGT substrates are selected. The first such complexes contained peptides derived from the HCF-1 cleavage region (PDBs 4N3A, 4N3B, 4N3C) (Figure 2b left panel) [33].
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br Acknowledgements br Tuliposides Pos the major
2020-08-04
Acknowledgements 6-Tuliposides (Pos), the major secondary metabolites in tulip (), are glucose esters of 4-hydroxy-2-methylenebutanoate and (3)-3,4-dihydroxy-2-methylenebutanoate; the former and the latter are referred to as PosA and PosB, respectively ()., , PosA and PosB serve as precursors
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We thank Unni Larsen for technical assistance and Raoul
2020-08-04
We thank Unni Larsen for technical assistance and Raoul C.M. Hennekam and Karen Brøndum-Nielsen for professional assistance. The work was supported by grants from the Western Norway Regional Health Authority (911977 and 912161 to C.B.), the Dr. Jon S. Larsens Foundation (to C.B.), and the Olav Raag
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br Results and discussions Fig depicts the trajectory of
2020-08-04
Results and discussions Fig. 10 depicts the trajectory of a gun drill chip. As soon as the chip breaks away from the cutting edges (Fig. 10a), it is carried by the coolant towards the wall of the hole (Fig. 10b), resulted in the first collision (Fig. 10c). The chip is then rebounded from the wall
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DbH activity was followed by oxymetry and we
2020-08-04
DbH activity was followed by oxymetry, and we showed that tyramine was responsible for a partial protection from H2O2-mediated inactivation. Since a peroxo-copper WEHI-539 hydrochloride could form, samples of DbH incubated with H2O2 and tyramine were probed for activity by HPLC, but octopamine coul
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br Funding source s This work
2020-08-04
Funding source(s) This work was supported by NIH MH107648 to E.G. Conflicts of interest Introduction Maternal behavior in rats involves dramatic changes in the perceptional, emotional and motivational responses of female rats towards infant rats (Numan and Young, 2016). Through mother-infa
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At the cellular level TGF has been involved in the
2020-08-03
At the cellular level, TGF-β1 has been involved in the formation of invadosomes (Mandal et al., 2008, Varon et al., 2006). Invadosomes are actin-based structures involved in matrix degradation and cell invasion through metalloproteinases (MMP) activity (Linder et al., 2011). Invadosomes, constitutiv
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The tonic immobility TI response is an innate
2020-08-03
The tonic immobility (TI) response is an innate and reversible defensive response characterized by profound physical inactivity and relative lack of responsivity to environmental stimuli (Klemm, 2001, Ratner, 1967). This behavior is shown during situations of extreme, inescapable threat (Gallup, 197
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Analysis of Western blots of thrombocyte lysates
2020-08-03
Analysis of Western blots of thrombocyte lysates showed differential presence of activated phosphorylated forms of ERK1/2, p38 and NFκB. LPS simultaneously induces gene SM-406 and subsequent activation of a MAPK Phosphatase (DUSP 5/8) as p38 and others are activated in the cell. Lower signal of P-E
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br ILCs as chemosensory cells The Aryl Hydrocarbon Receptor
2020-08-03
ILCs as chemosensory cells The Aryl Hydrocarbon Receptor (AHR) is a ligand-activated TF that binds indoles derived from the bacterial degradation of dietary tryptophan, as well as tryptophan metabolites contained in vegetables [79], bacterial toxins [] and environmental polycyclic hydrocarbons (F
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Our findings present the possibility that inhibition of DGK
2020-08-03
Our findings present the possibility that inhibition of DGKε could be a target for cancer therapy. This strategy could be particularly effective for PHA-767491 tumors, since the brain has a high expression of DGKε. There is a human disease that has been shown to be associated with a mutation of the
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Ac-YVAD-CHO mg Because of growing concerns about the potenti
2020-08-03
Because of growing concerns about the potential adverse impacts of pharmaceuticals on non-target aquatic organisms, DEX was prioritized by ranking schemes for environmental risk assessment (Roos et al., 2012); it is prescribed for its potent glucocorticoid effect. Several recent studies investigated
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Microarray analysis Total RNA from DT and
2020-07-31
Microarray analysis. Total RNA from DT40 and DT40YB1+/− cells was isolated using guanidine isothiocyanate (GITC)–phenol method [25] and poly(A+) RNA was purified using oligo(dT) cellulose column following standard procedures [24]. Two DNA microarrays of 120 human cell cycle-related genes were purcha
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