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Our module is designed to allow in process
2021-01-30
Our module is designed to allow in-process measurement of [C]-tracer molar activity (MA, GBq/μmol at EOB) using a Streptomycin sulfate detector with a UV detector at the outlet of the HPLC-portion of the system. In the HPLC chromatogram, peak analysis of the chromatographic data utilized PeakSimple
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The present study intended to characterize the
2021-01-30
The present study intended to characterize the predominant cholinesterasic form found in tissues of three tropical fish species, namely Phalloceros harpagos Lucinda, 2008 (common name guaru), Pterygoplichthys pardalis Castelnau, 1855 (common name cascudo) and Astyanax altiparanae Garutti and Britski
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Among the different factors that
2021-01-30
Among the different factors that modulate Schwann cell biology, several studies pointed out the role played by neuroactive steroids, in particular progesterone (P4) and its derivatives dihydroprogesterone (DHP) and allopregnanolone (ALLO). Schwann P7C3 are steroidogenic, possessing the entire enzym
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br Enzyme catalysis A biochemically
2021-01-30
Enzyme catalysis A biochemically spontaneous process proceeds in a direction where free N-3-oxo-dodecanoyl-L-Homoserine lactone of the system decreases. However, every spontaneous or energetically favorable reaction needs to overcome an energy barrier known as the activation energy barrier becau
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Central to the mechanism of cold I
2021-01-30
Central to the mechanism of cold I/R-associated liver injury is the activation of the pro-inflammatory cascade resulting in the release of pro-inflammatory cytokines. In agreement with the present study, serum and hepatic mRNA levels of TNF-α, IL-6, and ICAM-1 were all significantly up-regulated ear
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bapta am br Discussion The aim of this study was to establis
2021-01-30
Discussion The aim of this study was to establish staining protocols to enhance the visualization of a dental filling or its remaining in forensic dentistry. Teeth and dental materials resist to most of environmental and disaster conditions, therefore the forensic odontology exam is essential in
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DGK is also involved in cell differentiation Previously to
2021-01-29
DGKδ is also involved in cell differentiation. Previously, to investigate the physiological roles of DGKδ, DGKδ-deficient mice have been generated. On the basis of the analysis of DGKδ-deficient mice, Crotty et al. reported that DGKδ regulates the epidermal growth factor receptor (EGFR) pathway by a
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Within the BLA both CRF and the CRF
2021-01-29
Within the BLA, both CRF and the CRF1 receptor have been shown to functionally regulate synaptic activity. In vivo, CRF release into the BLA originates from projections from the CeA (Roozendaal, Brunson, Holloway, McGaugh, & Baram, 2002). Central administration of both CRF and CRF1 agonists has been
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br Discussion Cytomegalovirus CMV is
2021-01-29
Discussion Cytomegalovirus (CMV) is a herpes virus that causes primary infection in normal hosts and re-activation infection in compromised hosts with impaired CMI, e.g., organ transplants. Following primary infection, which may be severe, CMV becomes latent in lymphocytes. Reactivation may occur
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Exon encodes a section of the extracellular ligand binding
2021-01-29
Exon 3 encodes a section of the extracellular ligand-binding domain and two variants in the 5′ region were first identified in Drosophila melanogaster (Semenov and Pak, 1999). These variants were initially termed modules 1 and 2 and correspond to exons 3a and 3b, respectively. To date, exon 3 altern
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br torsion is a urological emergency
2021-01-29
torsion is a urological emergency that may occur at any age. To establish blood flow surgical detorsion is required in most cases while detorsion can sometimes be achieved by hand assistance. Regardless of the correction method 2 phases (I/R) negatively affect germ cells. The torsion phase decreas
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Interestingly anti inflammatory actions for sPLA V were
2021-01-29
Interestingly, anti-inflammatory actions for sPLA2-V were also described in mice a few years ago in a model of autoimmune complex mediated arthritis [148]. A novel mechanism was delineated, whereby sPLA2-V promotes phagocytosis of immune complexes by macrophages to ameliorate inflammation in autoimm
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To analyze EBI expression and its function in T
2021-01-29
To analyze EBI2 expression and its function in T cells in vivo, we created an EGFP reporter/knockout mouse strain, termed EBI2EGFP. This mouse strain in heterozygous configuration allows for a systematic analysis of the expression of EBI2 in distinct cell types in steady-state and under inflammatory
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Sarpogrelate hydrochloride In contrast to SQLE HMGCR
2021-01-29
In contrast to SQLE, HMGCR could be efficiently degraded in Sarpogrelate hydrochloride lacking UBE2J2. However, this was not the case in cells devoid of UBE2G2, as these cells were unable to support 25-hydroxycholesterol (25-HC)-stimulated degradation of HMGCR (Fig. 1C). This finding is consistent
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Current therapeutic interventions are directed both to preve
2021-01-29
Current therapeutic interventions are directed both to prevent (primarily by proper glycemic control) and to treat the advanced stages of diabetic retinopathy, when vision has already been significantly affected. Although these therapies can be very effective in preventing, delaying or reducing visi
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