• Anti inflammatory potential of OPE was evaluated by the

  2018-10-22

  

  Anti-inflammatory potential of OPE-4 was evaluated by the nutrigenomic method [24,25]. In the past two decades, different cell-based and animal models have been used to analyze the effects of test extracts on soluble guanylate cyclase of genes related to a variety of diseases, a discipline called n

• Introduction The intestinal tract of adult carries kg of

  2018-10-22

  

  Introduction The intestinal tract of adult carries 1–2kg of microbes. It is a common knowledge that pathogenic microbes could cause infectious diseases such as diarrheal, while others are associated with inflammatory and allergic diseases [1–3]. On the other hand, the majority of the gut microbes

• br Introduction Diverse types of protease inhibitors

  2018-10-22

  

  Introduction Diverse types of protease inhibitors (PIs) have been isolated, characterized, and evaluated for their biological potentials. They are small molecular mass peptides capable of inhibiting endogenous proteases. Plant PIs fascinates the attention of researchers because of their increasin

• Phytochemicals including polyphenols and saponins are promin

  2018-10-22

  

  Phytochemicals including polyphenols and saponins are prominent for their diverse health benefits including antioxidant and antidiabetic activities [44]. In this study, polyphenolics (total phenolics, tannins and total flavonoids) and total saponins were quantified in B. eurycoma and D. microcarpum

• Introduction A rapid change in the

  2018-10-22

  

  Introduction A rapid change in the dietary lifestyle has been observed since few years along with urbanization, globalization and economic development leading to increase in the number of people suffering from poor health, which is reflected by increased incidence of diseases such as obesity, diabe

• br Materials and methods br Results and discussion

  2018-10-22

  

  Materials and methods Results and discussion Conclusions In conclusion, minimally processed beetroot can effectively protect mayonnaise from lipid oxidation during storage at 4°C for 28 days. TBARS and Rancimat results showed that the antioxidant capacity of microwaved beetroot conferred a

• br Experimental Procedures br Acknowledgments We thank

  2018-10-22

  

  Experimental Procedures Acknowledgments We thank Richard Davis, Stefan Braam, and Dorien Ward for advice and protocols for the spin EB differentiation method, and for discussions about the data. We also thank Arie Verkerk for help with manuscript preparation, and David Hood (York University, O

• Similar to our observation that Nanog

  2018-10-22

  

  Similar to our observation that Nanog−/− iPSCs could give rise to chimeric animals, Nanog null ESCs have been shown to contribute to the three germ layers (Chambers et al., 2007). However, in the case of ESC chimeras, Nanog−/− GFP+ liver x receptor were not detected in the germline after E12.5. Bec

• NODAL plays pleiotropic roles in the

  2018-10-22

  

  NODAL plays pleiotropic roles in the early embryo. Expression can be detected in the inner cell mass and persists throughout the epiblast until axis specification, when it becomes restricted to the proximal posterior region (Conlon et al., 1994; Mesnard et al., 2006). NODAL activity relies on pro-pr

• br Materials and methods br Results br Discussion

  2018-10-20

  

  Materials and methods Results Discussion Genotoxic stress and DNA damage are considered to be major causes of aging in mammals. The risk of mutation load and loss of genome integrity in adult stem cells has been proposed to be the principal cause of age related decline in tissue function (R

• br Molecular changes associated with cell cycle

  2018-10-20

  

  Molecular changes associated with THZ531 withdrawal have been described, but molecular mechanisms of terminal differentiation remain largely uncharacterized The transition to the terminally differentiated phenotype is accompanied by down-regulation of cell cycle factors and up-regulation of cell

• br Materials and methods br Results There are a

  2018-10-20

  

  Materials and methods Results There are a number of complex methods for the generation of neural subtypes from hESCs and iPSCs. In most of them, intact pluripotent colonies are first lifted, induced to form EBs, and then grown in the presence of lineage specific morphogens and growth factors t

• p-Cresyl sulfate It is now well established that hypoxia bet

  2018-10-20

  

  It is now well established that hypoxia between 1% and 5% oxygen facilitates induction and maintenance of immature cellular phenotypes ranging from mesenchymal stem p-Cresyl sulfate to satellite cells and embryonic stem cells (Prasad et al., 2009; Yang et al., 2012), and it appears that this effect

• br Methods br Results br Discussion Originally human bone

  2018-10-20

  

  Methods Results Discussion Originally, human bone marrow-derived CD34+ faah inhibitor were defined as hematopoietic stem/progenitor-rich cells, while endothelial progenitor cells (EPCs), which play an important role in post-natal angiogenesis/vasculogenesis in ischemic tissues, have also be

• br Acknowledgments br This work was supported by the

  2018-10-20

  

  Acknowledgments This work was supported by the National Institutes of Health grant 5UO01DK089569-05 (Beta Cell Biology Consortium/M.G.) and The Leona M. and Harry B. Helmsley Charitable Trust grant 2012PG-T1D010 (M.G.) Introduction Astrocytes are the most abundant cell type in the human bra

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