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However there are several limitations to these
2019-04-28
However, there are several limitations to these findings. Current diagnostic practice, especially the frequency, timing, and accuracy of clinical diagnoses or empirical tuberculosis treatment, is highly setting-specific, dependent on adherence to the WHO algorithm for smear-negative tuberculosis, an
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Defensas comprensibles en un medio en que los libros europeo
2019-04-28
Defensas comprensibles en un medio en que los libros europeos pulularon, entre ellos una vieja novela como Las aventuras de Telémaco (1699) de François Fénelon, que al parecer se puso muy de moda entre los curas neogranadinos: en Patía varios de ellos le preguntaron al francés Boussingault si lo hab
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CD is a type I
2019-04-28
CD147 is a type I transmembrane glycoprotein of the immunoglobulin superfamily. CD147 has been reported to regulate the expression of P-gp and affect apoptosis in cancer sglt-2 with MDR phenotype [10,13,14]. In the present study, drug-free K562/ADR was first established by culturing K562/ADR in med
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We would like to highlight that these
2019-04-28
We would like to highlight that tubulin these differences need to be considered also at a regional level, and not only regarding screening but also treatment. In Spain, the European country with the highest prevalence of Chagas disease, the health-care system legislation varies among the different
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br Conventional mapping and ablation of ventricular tachycar
2019-04-28
Conventional mapping and ablation of ventricular tachycardia Substrate mapping during sinus rhythm Technical issues Conclusion Conflict of interest Introduction By eliminating the arrhythmogenic focus, catheter ablation can be a curative therapy of ventricular tachyarrhythmias (VTA
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O processo de sele o
2019-04-28
O processo de seleção é crucial, pois elastase inhibitor ‘escolhida’ será a responsável, nos próximos cinco anos, pela gestão do hospital determinado, decisão publicada em Diário Oficial. Dois aspectos são merecedores de atenção. Inicialmente, a decisão unilateral de escolha pelo Secretário de Saúde
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Splicing machinery dysfunctions have been associated
2019-04-28
Splicing machinery dysfunctions have been associated to CLL, in particular gene mutations (splicing factor 3B subunit 1) which are present in about 15% of patients . To our knowledge, no gene mutation has ever been detected in CLL. In order to broaden our knowledge on the frequency of splicing mu
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hmg-coa reductase inhibitor br Conclusion br Introduction Mu
2019-04-28
Conclusion Introduction Multiple myeloma is a malignant plasma cell disorder, comprising approximately 10% of all haematological malignancies, and its incidence is increasing [1]. The pathogenesis is complex, culminating in malignant transformation of clonal plasma cells. The aetiology is not
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br Cholera remains a serious global public health
2019-04-26
Cholera remains a serious global public health problem, disproportionately affecting poor individuals, causing illness and death for thousands of people each year. Cholera cases are on the rise, with 47% more cases reported to WHO in 2014 than in 2013. Innovative approaches to control the disease
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We have received funding from the Wellcome Trust to develop
2019-04-26
We have received funding from the Wellcome Trust to develop a global atlas of podoconiosis. We aim to advance new knowledge on the geographical distribution and spatial epidemiology of the disease. A first step in this work will be to establish the geographical absence of disease by applying an evid
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br Ablation strategies from targeted to homogenization The t
2019-04-26
Ablation strategies – from targeted to homogenization The techniques and principles originally developed in postinfarction scar have been translated and applied to patients with various etiologies of fibrosis and confluent scar including Chagasic cardiomyopathy, nonischemic cardiomyopathy, arrhyt
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br Conflict of interest br Introduction Nasopharyngeal
2019-04-26
Conflict of interest Introduction Nasopharyngeal carcinoma (NPC) is a tumor arising from the epithelial cells that line the surface of the nasopharynx. It is a commonly found tumor of the head and neck region in adults, and its incidence varies widely in different regions. It has been observed
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br Conclusions br Limitation br Acknowledgments This researc
2019-04-26
Conclusions Limitation Acknowledgments This research was supported in part by the China Postdoctoral Science Foundation (Nos. 2013M542478 and 2015T81139), a Grant (no. 2014FB059) from the Joint Special Funds for the Department of Science and Technology of Yunnan Province-Kunming Medical Uni
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We used MRI images taken to weeks after a crisis
2019-04-26
We used MRI images taken 1 to 8 weeks after a crisis to explore basal ganglion involvement and found restricted caffeic acid phenethyl ester at the basal ganglion. This finding suggests that cytotoxic damage to the basal ganglion persists post-crisis. When MRI images were obtained much longer after
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br Mechanisms of ventricular fibrillation electrical storm i
2019-04-26
Mechanisms of ventricular fibrillation/electrical storm in the Brugada syndrome patients One of the most consistent features of BrS is that premature ventricular contraction (PVC), which triggers VF, is almost always short-coupling [3,4]. An interesting phenomenon is that many of the VF episodes
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