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Given the vast number of
2018-11-09
Given the vast number of tests, measures, and stimuli in the test battery, it Tariquidar is unlikely that specific stimuli or responses were recalled, although items could be more readily recognized even after 1year. Thus, episodic recognition or recall of specific test items could only partially ac
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Regions of linkage disequilibrium LD were
2018-11-09
Regions of linkage disequilibrium (LD) were defined for the three loci tagged by SNPs reaching genome-wide significance. rs17599026, associated with urinary frequency, tags a 106kb region of LD (base position 137,657,783–137,763,798; Fig. 2A) containing part of KDM3B (including the promoter region
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br HEV Mutations and Their Functional
2018-11-09
HEV Mutations and Their Functional Role RNA viruses exhibit high genetic variability by rapid evolution with estimated mutation rate ranging from 10 to 10 substitutions per nucleotide per strand copying (Sanjuan et al., 2010). The HEV mutation rates were estimated indirectly from clinical isolate
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Previous preclinical research on brain development and disea
2018-11-09
Previous preclinical research on orexins development and disease has primarily assessed morphological changes or alterations at the receptor level. These studies have yielded critical information about adolescent biology and behavior. There is little known, however, about real-time dynamics of neuro
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Behavioral studies indicate peak sensitivity to
2018-11-09
Behavioral studies indicate peak sensitivity to reward during adolescence (Cauffman et al., 2010), yet neuroimaging results have been inconsistent. Functional magnetic resonance imaging (fMRI) studies have shown developmental peaks in striatal activation when processing rewards (Ernst et al., 2005;
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br Methods br Results br Discussion The
2018-11-09
Methods Results Discussion The notion of trait hypoactivation in right aTPJ is intriguing given the temporoparietal junction\'s well-established roles in both social and attentional processes (for reviews see Carter and Huettel, 2013; Decety and Lamm, 2007). Due to the social nature of the
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raas inhibitor Una clara expresi n de la frivolidad
2018-11-09
Una clara expresión de la frivolidad intelectual que en este aspecto anima a la elite de economistas neoliberales la proporciona la cándida manera de reflexionar del reconocido «Chicago-boy» Cristián Larroulet contenida en su libro Chile camino al desarrollo, escrito cuando aún era miembro del gabin
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For other regions however the reduction in transport costs
2018-11-09
For other regions, however, the reduction in transport costs provided by railways had diverse consequences leading to the specialization in agriculture and to the loss of competitiveness in manufacturing and handcraft production which were previously protected by the high transport costs (Cano, 1977
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As p is essential for many human
2018-11-09
As p38 is essential for many human malignancies including CRC, some p38is have been tested in early stage human cancer clinical trials (https://clinicaltrials.gov). To date, however, positive results have not been reported. It has become clear that due to inter-patient and intra-patient heterogeneou
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In relation to SSEA expression the differentiation threshold
2018-11-08
In relation to SSEA3 expression, the ‘differentiation threshold’ may lie at different points along the linear path of differentiation (Fig. 4) depending on the cell line and the culture conditions used to propagate undifferentiated ES cells. In comparison to normal human ES cells, the adapted human
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Hence we propose a model in which transient
2018-11-08
Hence, we propose a model in which transient HES5 activity in early mesoderm instructs the timing of cardiac fate specification while repressing the first wave of hematopoiesis. Thus in the absence of this signal, commitment to EryP is favored by default. Moreover, after a pulse of Hes5 instructing
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br Results Hepatocytes were successfully isolated from hepat
2018-11-08
Results Hepatocytes were successfully isolated from 70 hepatic tissues; 35 were obtained from organ donors (OD) rejected for OLT, and 35 were tissues were obtained from the explanted liver of patients who received OLT for metabolic and other types of liver disease (MD) including, biliary atresia,
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br Conclusion Human BMSCs are a promising cell
2018-11-08
Conclusion Human BMSCs are a promising cell type for regenerative medicine and tissue-engineering applications. They have the capacity for self-renewal and exhibit multipotent differentiation potential through which they can produce lineages such as osteoblasts, chondrocytes, and adipocytes (Char
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eicosapentaenoic acid Supplier br Materials and methods br R
2018-11-08
Materials and methods Results Discussion The current work showed that M3O-SKM allows for the establishment and maintenance of iPSCs in the absence of exogenous LIF. We also showed that miR-205-5p synergizes with M3O-SKM. More than 20 individuals or families of miRNAs play critical roles in
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br Gene editing using ssODNs
2018-11-08
Gene editing using ssODNs as donors Although a remaining loxP or FRT site may in many cases not influence endogenous gene regulation, and the excision of a PB transposon in most cases leads to restoration of the WT sequence, footprintless gene correction using ssODNs as donors is considered as th
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