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br Quantitative analysis The quantitative
2019-06-12
Quantitative analysis The quantitative analysis is based on modeling the concentration change of the contrast agent using pharmacokinetic modeling techniques. An initial conversion of SI to concentration values is needed. Concentration vs time curves are then fitted using a bi-compartmental PK mo
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Graft versus host disease prophylaxis included tacrolimus my
2019-06-12
Graft versus host disease prophylaxis included tacrolimus, mycophenolate mofetil and post transplant cyclophosfamide (50mg/kg on days +3 and +4) as previously proposed by Baltimora׳s group. After a follow up of 18 months patient is in good clinical conditions, in persisting complete remission as es
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br Discussion ATRA and arsenic are both known
2019-06-12
Discussion ATRA and arsenic are both known to induce differentiation syndrome but this case was notable for its severity. Previous studies of differentiation syndrome have demonstrated that APL Pyrrolidinedithiocarbamate ammonium treated with ATRA secrete the chemokines CCL2 and IL-8, which in c
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Atrial fibrillation AF is the most common type of
2019-06-12
Atrial fibrillation (AF) is the most common type of arrhythmia in developed countries. Its prevalence almost doubles with each decade of life [1], with a lifetime prevalence of 25% [2]. AF is also an important risk factor for mortality [3]. Along with stroke, heart failure (HF), which is a signific
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Another mechanism is that J waves represent a repolarization
2019-06-12
Another mechanism is that J waves represent a repolarization abnormality where J waves are created by the transmural voltage gradient [16]. During myocardial ischemia, the membrane ionic currents are known to be augmented, in turn augmenting the transient outward current (Ito). Augmented Ito would r
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A year old man was hospitalized following a first syncope
2019-06-12
A 36-year-old man was hospitalized following a first syncope attack while awake at night. No history of sudden death was reported in his family. On arrival, his consciousness was clear and his vital signs were stable. An electrocardiogram (ECG) showed sinus rhythm with ST-segment elevations and J wa
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LBH 589 Estes exemplos s o iniciativas importantes para term
2019-06-12
Estes exemplos são iniciativas importantes para termos um esboço da relação entre LBH 589 Igreja católica e a política no Brasil durante primeiras décadas do século xx. Elas denotam certo poder de resistência da instituição frente a possíveis ameaças de sua hegemonia como provedora de um estatuto mo
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br Conclusions br Acknowledgements This work was
2019-06-11
Conclusions Acknowledgements This work was supported by Bloodwise, the International Myeloma Foundation and a Marie Curie Career Integration Grant from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° [294160]. The osteoblast in normal bone physiology
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Expresi n de la complejidad de
2019-06-11
Expresión de la complejidad de esta articulación de los movimientos de la región en este proyecto es, además, la gestación —de forma paralela A-1210477 los cms, desde 2009— de la Articulación Continental de Movimientos Sociales hacia el alba, cuyo punto de partida es la “Carta de los Movimientos Soc
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This patient s shortest R R interval on ECG was
2019-06-11
This patient\'s shortest R–R interval on ECG was about 200ms (300bpm), which indicated high risk of sudden cardiac death. The patient underwent catheter ablation. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias [1], which include accessory pathway-mediated arr
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Major outcomes from MADIT II trial
2019-06-11
Major outcomes from MADIT-II trial suggested that, once again, the risk of death in defibrillator group was significantly less than conventional-therapy group with hazard ratio of 0.69. In this trial, the major drawback was corrected. The medication use remained balanced between ICD patients, and co
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The deletion of q seen
2019-06-11
The deletion of 14q seen in our patient included the IGH locus at 14q32.33. This is noteworthy, because loss of 14q has been reported as a recurrent aberration acquired during the natural history of CLL. The acquisition of a del(14) may thus be indicative of CLL in transformation. In a study of a la
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br Comments The present two cases developed ACC
2019-06-11
Comments The present two cases developed ACC during chemotherapy induced neutropenic for AML. ACC is a relatively rare complication in these patients’ population. It’s reported in 0.4% among all neutropenic episodes of patients with acute leukemia or aggressive lymphoma undergoing myelosuppressiv
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Most women were found to
2019-06-11
Most women were found to be unaware of possible prevention of the disease, including screening services for early detection and treatment of precancerous lesions. Some women affected by CC tend to initially seek treatment from traditional healers and use holy water. Beliefs concerning the cause of t
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RANK RANKL The RANK RANKL signaling pathway
2019-06-11
RANK/RANKL: The RANK/RANKL signaling pathway is a critical component of both normal and malignant bone remodeling. RANK is a transmembrane signaling receptor and a member of the tumor necrosis receptor (TNF) superfamily that is found on the surface of OCL precursors [43,44]. RANK ligand (RANKL) is e
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