br Results br Discussion In previous studies we derived

2018-10-20

Results Discussion In previous studies, we derived pericytes (Kusuma et al., 2013) and both hiPSC syn-vSMCs and hiPSC con-vSMCs (Wanjare et al., 2013a). In performing direct comparisons between these perivascular cell derivatives, we observed numerous differences that enable the study of huma

No effective therapies are available

2018-10-20

No effective therapies are available for motor neuron diseases, including SMARD1. Neural stem cell (NSC) transplantation represents a possible therapeutic strategy for ameliorating the neurological phenotype by multiple mechanisms, including neuroprotection and cell replacement of different CNS ghre

These fate analyses relied on

2018-10-20

These fate analyses relied on the restriction of Krox20 expression to BC src inhibitors during early PNS development. However, from embryonic day 15.5 (E15.5), Krox20 also is expressed in Schwann cells (Topilko et al., 1994), thereby preventing later analysis of BC derivatives. To circumvent this p

Emerging evidence suggests that paracrine factor profiling o

2018-10-20

Emerging evidence suggests that paracrine factor profiling of MSCs is highly dependent on the microenvironment (Gao et al., 2016). Paracrine factors of iPSC-MSCs are reported to effectively rescue Dox-induced CM damage (Zhang et al., 2015). Nevertheless, how the therapeutic efficacy of MSCs is incre

Hello world!

2018-07-29